5 Essential Elements For cees dekker
5 Essential Elements For cees dekker
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Rotary motion of DNA rotors on nanopores. Top row: Uncooked video clip of the Cy5 channel of every rotor. Middle row: corresponding solitary-particle localization results of both equally ends with the DNA rotors. The placement of the present frame is marked as orange and blue dots, as well as trajectory of the 10 frames before The present body is proven as good traces.
Human Rad51 filaments on double- and one-stranded DNA: correlating normal and irregular varieties with recombination function.
Multicolor imaging of the bacterial nucleoid and mobile division proteins with blue, orange, and in the vicinity of-infrared fluorescent proteins
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola
This yielded a breakthrough. In just just a few months, we were capable to measure transportation through someone single-walled carbon nanotube. Determined by reduced-temperature experiments by a superb PhD pupil in my team, Sander Tans (now a valued colleague and professor at Delft College of Technological innovation with an Energetic investigate lab at AMOLF in Amsterdam), we showed that carbon nanotubes were being real quantum wires with pretty lengthy (micrometres) Digital coherence lengths — confirming theoretical predictions of metallic conduct.
Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of a single wire bridging two electrodes
‘At the outset we checked out biological programs which has a physical check out and acted on The idea of your resources we understood. It took a several years right before we began Doing work extra on the massive biological concerns. I then started to simply call it nanobiology, a time period that didn't exist at time.
2011, first in vitro measurements of transportation throughout an individual biomimetic nuclear pore intricate; improvement of multiplexed magnetic tweezers for kilo-molecule experiments; and resolved the system of homology recognition in DNA homologous recombination
2003, shown the 1st biosensors built outside of a carbon nanotube; solved the construction and mechanism of DNA maintenance proteins; and discovery of a completely new procedure for fabricating reliable-condition nanopores for DNA translocation
Dekker begun his exploration on solitary carbon nanotubes in 1993 when he setup a new line of exploration to study electrical transportation by means of single organic and natural molecules among nanoelectrodes. In 1996 a breakthrough was recognized with carbon nanotubes. This was achieved in a very collaboration With all the team of Nobel laureate Richard Smalley. STM and nanolithography strategies were accustomed to demonstrate that these nanotubes are quantum wires at The only-molecule level, with remarkable physical Houses.
Since 2000 he moved to solitary-molecule biophysics and nanobiology, with study from studies of DNA loop extrusion and supercoiling to DNA translocation as a result of nanopores. A lot more recently his investigation has focused on finding out chromatin structure and mobile division with bacteria on chip, even though he can also be aiming to in the end Make synthetic cells from The underside up.
Nanoscientist Cees Dekker is undoubtedly an amiable and flamboyant gentleman who appears much young in comparison to the 62 several years he truly is – fashionable Eyeglasses, psychedelic shirt, participating smile ceesdekker – but not a person to squander time. He will take his time, but no more than vital.
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Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij met enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond smart style and design in 2005. (nl)